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D.O.A. for the A.D.D. afflicted

I've been hearing trailers for this one all week…
Crank:
A hit man learns that a poison injected into his body will kill him if his heart rate drops slows a certain point. Now he must exact his revenge on the people who injected him before he takes his last breath.
(I just discovered this is one of the big movies opening this weekend. Wow, talk about summer going out with a whimper.)

But what really amuses me is how much this sounds like this movie (and it's various incarnations):
D.O.A.
1950 version (D.O.A.) with Edmond O'Brien and Pamela Britton: Small-town accountant Frank Bigelow goes to San Francisco for a week's fun prior to settling down with fiancée Paula. After a night on the town, he wakes up with more than just a hangover; doctors tell him he's been given a "luminous toxin" with no antidote and has, at most, a week to live! Not knowing who did it or why, Bigelow embarks on a frantic odyssey to find his own murderer.
1969 version (Color Me Dead) with Tom Tryon & Carolyn Jones: A man discovers that he has been deliberately poisoned and hasn't long to live. In the short time he has left, he determines to find out who poisoned him and why.
1988 version (D.O.A.) with Dennis Quaid and Meg Ryan: Someone poisoned Dexter Cornell. He's got to find out who. He's got to find out why. He's got to find out now. In 24 hours, he'll be Dead On Arrival.
(I've actually seen that last one, but I can't remember a single moment. Apparently memorable.)

It's an interesting progression… in 1950, he had a few days to live. By 1988 he's down to 24 hours. Today, unless he can keep his adrenaline up, he's gone in 60 minutes. Life really is stuck in the fast lane. Perhaps the best part about this movie is the tagline from IMDB: "Poison in his veins. Vengeance in his heart." That's almost as good as Snakes on a Plane!

(Let me not get bogged down too much in science and logic but, if he's been poisoned, how is getting amped up on an adrenaline rush supposed to help? Won't it just circulate the poison faster? I'm just asking, you know?)

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